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The adaptive response modifies latency for...
Journal article

The adaptive response modifies latency for radiation-induced myeloid leukemia in CBA/H mice.

Abstract

We have investigated the effect of the adaptive response on acute myeloid leukemia (AML) induced in CBA/Harwell mice by a chronic radiation exposure. Groups of mice irradiated with a total dose of 1. 0 Gy at two different chronic dose rates (0.5, 0.004 Gy/h) had similar frequencies of AML. Compared to control animals that did not develop AML, irradiation at either of these dose rates did not change the longevity of the mice that did not die of …

Authors

Mitchel RE; Jackson JS; McCann RA; Boreham DR

Journal

Radiation Research, Vol. 152, No. 3, pp. 273–279

Publisher

JSTOR

Publication Date

September 1999

DOI

10.2307/3580327

ISSN

0033-7587