Falling Insulin Requirements and Adverse Pregnancy Outcomes in Women With Pre-pregnancy Diabetes [10D]

INTRODUCTION: A subset of women with pre-gestational diabetes experience a third-trimester fall in insulin requirements (IR). There is no consensus on whether this fall represents placental dysfunction or is a variant of normal third-trimester physiology. Our study sought to determine whether a third-trimester drop in IR is associated with adverse pregnancy outcomes. METHODS: This is a retrospective cohort study of women with type 1 and 2 …