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Prophylactic transfusion for pregnant women with...
Journal article

Prophylactic transfusion for pregnant women with sickle cell disease: a systematic review and meta-analysis

Abstract

Pregnancy in women with sickle cell disease is associated with adverse maternal and neonatal outcomes. Studies assessing the effects of prophylactic red blood cell transfusions on these outcomes have drawn inconsistent conclusions. The objective of this systematic review was to assess the effect of prophylactic compared with on-demand red blood cell transfusions on maternal and neonatal outcomes in women with sickle cell disease. A systematic …

Authors

Malinowski AK; Shehata N; D'Souza R; Kuo KHM; Ward R; Shah PS; Murphy K

Journal

Blood, Vol. 126, No. 21, pp. 2424–2435

Publisher

American Society of Hematology

Publication Date

November 19, 2015

DOI

10.1182/blood-2015-06-649319

ISSN

0006-4971