Journal article
The flamenco Locus Controls the gypsy and ZAM Retroviruses and Is Required for Drosophila Oogenesis
Abstract
In Drosophila, the as yet uncloned heterochromatic locus flamenco (flam) controls mobilization of the endogenous retrovirus gypsy through the repeat-associated small interfering (rasi) RNA silencing pathway. Restrictive alleles (flamR) downregulate accumulation of gypsy transcripts in the somatic follicular epithelium of the ovary. In contrast, permissive alleles (flamP) are unable to repress gypsy. DIP1, the closest transcription unit to a …
Authors
Mével-Ninio M; Pelisson A; Kinder J; Campos AR; Bucheton A
Journal
Genetics, Vol. 175, No. 4, pp. 1615–1624
Publisher
Oxford University Press (OUP)
Publication Date
April 1, 2007
DOI
10.1534/genetics.106.068106
ISSN
0016-6731
Associated Experts
Fields of Research (FoR)
Medical Subject Headings (MeSH)
AnimalsAnimals, Genetically ModifiedBase SequenceCadherinsDNA PrimersDrosophila ProteinsDrosophila melanogasterFemaleGene Expression Regulation, DevelopmentalGenes, InsectGenetic Complementation TestHeterochromatinMutagenesis, InsertionalOogenesisRNA, Small InterferingRetroviridaeTranscription Factors