Journal article
Quantitative muscle analysis in facioscapulohumeral muscular dystrophy using whole‐body fat‐referenced MRI: Protocol development, multicenter feasibility, and repeatability
Abstract
INTRODUCTION/AIMS: Functional performance tests are the gold standard to assess disease progression and treatment effects in neuromuscular disorders. These tests can be confounded by motivation, pain, fatigue, and learning effects, increasing variability and decreasing sensitivity to disease progression, limiting efficacy assessment in clinical trials with small sample sizes. We aimed to develop and validate a quantitative and objective method …
Authors
Widholm P; Ahlgren A; Karlsson M; Romu T; Tawil R; Wagner KR; Statland JM; Wang LH; Shieh PB; van Engelen BGM
Journal
Muscle & Nerve, Vol. 66, No. 2, pp. 183–192
Publisher
Wiley
Publication Date
August 2022
DOI
10.1002/mus.27638
ISSN
0148-639X