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Predictors of Placebo Induction Response and...
Journal article

Predictors of Placebo Induction Response and Remission in Ulcerative Colitis

Abstract

BACKGROUND & AIMS: High placebo response rates in clinical trials of ulcerative colitis (UC) have been reported previously. However, data from patient-level analyses are lacking. We assessed factors associated with clinical and endoscopic placebo response among placebo-treated patients in clinical trials of UC. METHODS: We performed a post hoc analysis of pooled clinical trial data from GEMINI-1, ACT-1, ACT-2, PURSUIT, ULTRA-2, OCTAVE-1, and …

Authors

Wong ECL; Dulai PS; Marshall JK; Jairath V; Reinisch W; Narula N

Journal

Clinical Gastroenterology and Hepatology, Vol. 21, No. 4, pp. 1050–1060.e9

Publisher

Elsevier

Publication Date

April 2023

DOI

10.1016/j.cgh.2022.08.015

ISSN

1542-3565