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Identification of a megaplasmid centromere reveals...
Journal article

Identification of a megaplasmid centromere reveals genetic structural diversity within the repABC family of basic replicons

Abstract

The basic replication unit of many plasmids and second chromosomes in the alpha-proteobacteria consists of a repABC locus that encodes the trans- and cis-acting components required for both semiautonomous replication and replicon maintenance in a cell population. In terms of physical genetic organization and at the nucleotide sequence level, repABC loci are well conserved across various genera. As with all repABC-type replicons that have been …

Authors

MacLellan SR; Zaheer R; Sartor AL; MacLean AM; Finan TM

Journal

Molecular Microbiology, Vol. 59, No. 5, pp. 1559–1575

Publisher

Wiley

Publication Date

March 2006

DOI

10.1111/j.1365-2958.2006.05040.x

ISSN

0950-382X