Journal article
Prevalence and risk of inappropriate dosing of direct oral anticoagulants in two Swiss atrial fibrillation registries
Abstract
BACKGROUND: Direct oral anticoagulants (DOACs) have a favourable risk-benefit profile compared to vitamin K-antagonists (VKAs) in atrial fibrillation (AF). Dosing is based on age, weight and renal function, without need of routine monitoring.
METHODS AND RESULTS: In two prospective, multicentre AF cohorts (Swiss-AF, BEAT-AF) patients were stratified as receiving VKAs or adequately-, under- or overdosed DOACs, according to label. Primary outcome …
Authors
Montrasio G; Reiner MF; Wiencierz A; Aeschbacher S; Baumgartner C; Rodondi N; Kühne M; Moschovitis G; Preiss H; Coslovsky M
Journal
Vascular Pharmacology, Vol. 147, ,
Publisher
Elsevier
Publication Date
December 2022
DOI
10.1016/j.vph.2022.107120
ISSN
1537-1891