Thrombotic Thrombocytopenic Purpura (TTP) Management at Foothills Medical Centre: A Retrospective Analysis Between 2005-2010 (Tertiary Centre, Calgary)

Abstract TTP is a rare condition of microangiopathic hemolytic anemia and thrombocytopenia with a reported incidence of 4 cases per million people. Untreated mortality is reported to be as high as 90%; plasma exchange (PLEX) has significantly reduced this to 28%. Given the heterogeneity in presentation and severity at diagnosis, there is a wide range of practice with regards to exchanges, management of refractory disease and …