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Estradiol Replacement as a Potential Enhancer of...
Journal article

Estradiol Replacement as a Potential Enhancer of Working Memory and Neuroplasticity in Hypogonadal Trans Women

Abstract

INTRODUCTION: The cognitive effects of cross-sex hormone therapy (CSHT) are not well understood. In cisgender individuals, sex hormone therapy can impact neurotransmitter levels and structural anatomy. Similarly, in gender-diverse persons, CSHT has been associated with neural adaptations, such as growth in brain structures resembling those observed in cisgender individuals of the same sex. Hormone-related changes in learning and memory, as seen …

Authors

Schneider MA; Malhotra D; Spritzer PM; Hatchard T; Minuzzi L; Frey BN; Haefner SA; Nicholson A; McKinnon M; Syan SK

Journal

Neuroendocrinology, Vol. 113, No. 5, pp. 489–500

Publisher

Karger Publishers

Publication Date

2023

DOI

10.1159/000527130

ISSN

0028-3835