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Fabrication of succinate-alginate xerogel films...
Journal article

Fabrication of succinate-alginate xerogel films for in vitro coupling of osteogenesis and neovascularization

Abstract

The osseointegration of metallic implants is reliant on a cascade of molecular interactions and the delivery of macromolecules to the implant environment that occurs before substantial bone formation. Early blood vessel formation is a requisite first step in the healing timeline for osteoid formation, where vascular development can be accelerated as a result of controlled hypoxic conditioning. In this study, alginate-derived xerogel films …

Authors

Deering J; Lin DSY; D'Elia A; Zhang B; Grandfield K

Journal

Biomaterials Advances, Vol. 141, ,

Publisher

Elsevier

Publication Date

October 2022

DOI

10.1016/j.bioadv.2022.213122

ISSN

2772-9516