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Joint Associations of Maternal-Fetal APOL1...
Journal article

Joint Associations of Maternal-Fetal APOL1 Genotypes and Maternal Country of Origin With Preeclampsia Risk

Abstract

RATIONALE & OBJECTIVES: Preeclampsia, which disproportionately affects Black women, is a leading cause of preterm delivery and risk for future hypertension and chronic kidney disease (CKD). Apolipoprotein L1 (APOL1) kidney risk alleles, common among Black individuals, contribute substantially to CKD disparities. Given the strong link between preeclampsia and CKD, we investigated whether maternal and fetal APOL1 risk alleles can jointly …

Authors

Hong X; Rosenberg AZ; Zhang B; Binns-Roemer E; David V; Lv Y; Hjorten RC; Reidy KJ; Chen TK; Wang G

Journal

American Journal of Kidney Diseases, Vol. 77, No. 6, pp. 879–888.e1

Publisher

Elsevier

Publication Date

6 2021

DOI

10.1053/j.ajkd.2020.10.020

ISSN

0272-6386