Chapter
Prostanoids
Abstract
In asthmatic patients, it is likely that PGDinf2/inf and TinfX/infAinf2/inf are involved in causing acute bronchoconstriction after stimuli such as inhaled allergen in asthmatic patients. PGDinf2/inf also promotes the chemotaxis of eosinophils and Th2 cells, as well as the release of Th2 cytokines through stimulation of CRTH2. Also, there is evidence that inhibitory prostaglandins are released by asthmatic airways, which reduces …
Authors
O'Byrne PM
Book title
Asthma and Copd Basic Mechanisms and Clinical Management
Pagination
pp. 275-282
Publication Date
October 30, 2008
DOI
10.1016/B978-0-12-374001-4.00023-7