Conference
Abstract # 1849 The role of immune system maturation in development of normal behavior in mice
Abstract
Previous studies demonstrated differences in behavior and brain biochemistry between germ-free and conventional mice. We showed that mono-colonization with E. coli induces similar changes in behavior as with complex microbiota. BDNF and cFos expression in the amygdala and hippocampus regions were also changed after mono-colonization. Furthermore, using permanent colonizer E. coli JM83 and transient colonizer E. coli HA107 (mutant form of E. …
Authors
Philip V; Lu J; Galipeau HJ; Verdu EF; McCoy KD; Macpherson AJ; Hapfelmeier S; De Palma G; Surette MG; Collins SM
Volume
57
Publisher
Elsevier
Publication Date
10 2016
DOI
10.1016/j.bbi.2016.07.128
Conference proceedings
Brain Behavior and Immunity
ISSN
0889-1591