Journal article
Dual Targeting Factors Are Required for LXG Toxin Export by the Bacterial Type VIIb Secretion System
Abstract
Bacterial type VIIb secretion systems (T7SSb) are multisubunit integral membrane protein complexes found in Firmicutes that play a role in both bacterial competition and virulence by secreting toxic effector proteins. The majority of characterized T7SSb effectors adopt a polymorphic domain architecture consisting of a conserved N-terminal Leu-X-Gly (LXG) domain and a variable C-terminal toxin domain. Recent work has started to reveal the …
Authors
Klein TA; Grebenc DW; Shah PY; McArthur OD; Dickson BH; Surette MG; Kim Y; Whitney JC
Journal
mBio, Vol. 13, No. 5, pp. e02137–e02122
Publisher
American Society for Microbiology
Publication Date
October 26, 2022
DOI
10.1128/mbio.02137-22
ISSN
2161-2129