Journal article
Structure, isolation, composition and reconstitution of the neuronal fusion pore
Abstract
Neuronal communication is dependent on the fusion of 40-50 nm in diameter synaptic vesicles containing neurotransmitters, at the presynaptic membrane. Here we report for the first time at 5-8A resolution, the presence of 8-10 nm in diameter cup-shaped neuronal fusion pores or porosomes at the presynaptic membrane, where synaptic vesicles dock and fuse to release neurotransmitters. The structure, isolation, composition, and functional …
Authors
Cho WJ; Jeremic A; Rognlien KT; Zhvania MG; Lazrishvili I; Tamar B; Jena BP
Journal
Cell Biology International, Vol. 28, No. 10, pp. 699–708
Publisher
Wiley
Publication Date
October 2004
DOI
10.1016/j.cellbi.2004.07.004
ISSN
1065-6995