Journal article
Increased Expression of Interleukin-13 Receptor in Ileum Associated With Nonresponse to Adalimumab in Ileal Crohn’s Disease
Abstract
BACKGROUND: The terminal ileum poses a predilection for Crohn's disease (CD) but is less susceptible to undergo healing to treatment with biologics and small molecules. This study aimed to evaluate histologic features associated with endoscopic remission (ER).
METHODS: This is a post hoc analysis of patients with moderately to severely active CD, defined as Crohn's disease activity index 220 to 450, and terminal ileal ulceration treated with …
Authors
Wong ECL; Yusuf A; Pokryszka J; Dulai PS; Colombel J-F; Marshall JK; Reinisch W; Narula N
Journal
Inflammatory Bowel Diseases, Vol. 29, No. 6, pp. 875–882
Publisher
Oxford University Press (OUP)
Publication Date
June 1, 2023
DOI
10.1093/ibd/izac157
ISSN
1078-0998