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Anticipatory hyperexcitability and tolerance to...
Journal article

Anticipatory hyperexcitability and tolerance to the narcotizing effect of morphine in the rat

Abstract

The role of Pavlovian conditioning in tolerance to the narcotizing effect of a high dose of morphine in the rat was examined. Initially, two groups received nine injections of morphine (40 mg/kg), and two groups received nine injections of saline. One group administered each substance was injected in one of two distinctive environments: the animal colony or a distinctive room. Subsequently, rats in all groups received five morphine injections …

Authors

Hinson RE; Siegel S

Journal

Behavioral Neuroscience, Vol. 97, No. 5, pp. 759–767

Publisher

American Psychological Association (APA)

Publication Date

October 1983

DOI

10.1037/0735-7044.97.5.759

ISSN

0735-7044