Journal article
Unequal α and β Globin mRNA in Reticulocytes of Normal and Mutant f/f Fetal Mice
Abstract
Messenger RNA (mRNA) was isolated from adult as well as normal and mutant f/f fetal mouse reticulocytes by poly-U affinity chromatography. mRNA from normal adult reticulocytes directed equal synthesis of alpha and beta globin chains in wheat germ cell free translational system. mRNA from either normal or mutant f/f fetal reticulocytes directed 40% more alpha globin synthesis than beta globin synthesis. These observations are suggestive that …
Authors
Chui DHK; Patterson And M; Bayley ST
Journal
British Journal of Haematology, Vol. 44, No. 3, pp. 431–439
Publisher
Wiley
Publication Date
March 1980
DOI
10.1111/j.1365-2141.1980.tb05913.x
ISSN
0007-1048