Journal article
Concentration-Dependent Structural Transitions of Human Telomeric DNA Sequences
Abstract
Oligodeoxyribonucleotides (ODNs) that have four repeats of the human telomeric sequence d(TTAGGG)(n) can assume multiple monomolecular G-quadruplex topologies. These are determined by the cation species present, the bases at the 5' or 3' end, and the sample preparation technique. In this work, we report our studies of the concentration dependence of the circular dichroism (CD) and the vibrational modes probed by Raman scattering of three …
Authors
Abu-Ghazalah RM; Rutledge S; Lau LWY; Dubins DN; Macgregor RB; Helmy AS
Journal
Biochemistry, Vol. 51, No. 37, pp. 7357–7366
Publisher
American Chemical Society (ACS)
Publication Date
September 18, 2012
DOI
10.1021/bi300689t
ISSN
0006-2960