Journal article
Asthma Control, Airway Mucus, and 129Xe MRI Ventilation After a Single Benralizumab Dose
Abstract
BACKGROUND: Patients with eosinophilic asthma often report poor symptomatic control and quality of life. Anti-IL-5 therapy, including anti-IL-5Rα (benralizumab), rapidly depletes eosinophils in the blood and airways and also reduces asthma exacerbations and improves quality of life scores. In patients with severe asthma, eosinophilic inflammation-driven airway mucus occlusions have been measured using thoracic x-ray CT imaging. Pulmonary 129Xe …
Authors
McIntosh MJ; Kooner HK; Eddy RL; Jeimy S; Licskai C; Mackenzie CA; Svenningsen S; Nair P; Yamashita C; Parraga G
Journal
Chest, Vol. 162, No. 3, pp. 520–533
Publisher
Elsevier
Publication Date
9 2022
DOI
10.1016/j.chest.2022.03.003
ISSN
0012-3692