Journal article
Development of spontaneous seizures over extended electrical kindling I. Electrographic, behavioral, and transfer kindling correlates
Abstract
The present study was aimed at evaluating an extended kindling model of spontaneous epilepsy. Behavioral and electrographic responses to repeated kindling of either the perforant path or amygdala were monitored for up to 300 trials. Kindling initially led to generalized convulsions equivalent to the level 5 seizure on the rating scale developed by Racine. The evoked seizures became progressively more complex with additional kindling, which was …
Authors
Michael M; Holsinger D; Ikeda-Douglas C; Cammisuli S; Ferbinteanu J; DeSouza C; DeSouza S; Fecteau J; Racine RJ; Milgram NW
Journal
Brain Research, Vol. 793, No. 1-2, pp. 197–211
Publisher
Elsevier
Publication Date
May 1998
DOI
10.1016/s0006-8993(98)00155-3
ISSN
0006-8993