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GABAergic modulation of neocortical long‐term...
Journal article

GABAergic modulation of neocortical long‐term potentiation in the freely moving rat

Abstract

Although the neocortex has generally been considered resistant to the induction of long-term potentiation (LTP), we have recently shown that LTP can be reliably induced in the freely moving rat provided that the stimulation sessions are spaced and repeated. Here, we report that the induction of LTP in this preparation can be modulated by both GABAergic agonism and antagonism. The delivery of stimulation trains in the presence of the GABA(A) …

Authors

Trepel C; Racine RJ

Journal

Synapse, Vol. 35, No. 2, pp. 120–128

Publisher

Wiley

Publication Date

February 2000

DOI

10.1002/(sici)1098-2396(200002)35:2<120::aid-syn4>3.0.co;2-6

ISSN

0887-4476