Journal article
Decreased Expression of Cerebral Dopamine Neurotrophic Factor in Platelets of Probable Alzheimer Patients
Abstract
BACKGROUND: Alzheimer disease (AD) patients experience progressive neurological and cognitive decline attributed to neurodegeneration. Cerebral dopamine neurotrophic factor (CDNF) has been identified to protect and rescue neurons in various preclinical neurodegeneration models. The expression of this protein occurs in both the central nervous system and peripheral blood. Blood platelets exhibit several biochemical impairments similar to the …
Authors
Joshi H; Shah J; Abu-Hijleh FA; Patel V; Rathbone M; Gabriele S; Gabriele J; Baranowski D; Molloy D; Frey BN
Journal
Alzheimer Disease & Associated Disorders, Vol. 36, No. 3, pp. 269–271
Publisher
Wolters Kluwer
Publication Date
7 2022
DOI
10.1097/wad.0000000000000488
ISSN
0893-0341