The status of glycolaldehyde in the biosynthesis of vitamin B6.

Competition experiments, employing 14C-labeled samples of glycerol and glycolaldehyde, indicate that in Escherichia coli B there are two independent pathways leading to pyridoxal. In mutant WG2 (and therefore presumably also in the wild strain) the major pathway utilizes glycerol and related trioses as the sole carbon source in the construction of the C8N skeleton of pyridoxol: C-1, -3 of glycerol yields C-2', -3, -4', -5' and -6, C-2 of …