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Noninferiority Randomized Controlled Trials
Journal article

Noninferiority Randomized Controlled Trials

Abstract

From 2005 to 2015, the publication of noninferiority trials increased by six-fold. Noninferiority trials assess whether a new treatment's efficacy is comparable with that of the standard of care and have several appeals. Noninferiority trials can evaluate for both noninferiority and superiority of a new treatment. In addition, multiple treatment modalities exist, and new treatments may be advantageous for reasons beyond efficacy. Common …

Authors

Kim KS; Chan A-W; Belley-Côté EP; Drucker AM

Journal

Journal of Investigative Dermatology, Vol. 142, No. 7, pp. 1773–1777

Publisher

Elsevier

Publication Date

July 2022

DOI

10.1016/j.jid.2022.04.015

ISSN

0022-202X