Journal article
Abstract 669: SR-BI in Bone Marrow--Derived Cells Protects Mice From Diet-Induced Coronary Artery Atherosclerosis and Myocardial Infarction
Abstract
Background: SR-BI deficient, apolipoprotein E hypomorphic mice develop diet induced occlusive coronary artery atherosclerosis, myocardial infarction and early death. Methods: To test the role of SR-BI in bone marrow derived cells, SR-BI-null; apoE- hypomorphic mice were transplanted with SR-BI +/+ apoE-hypomorphic, or control, autologous SR-BI-null; apoE-hypomorphic bone marrow. Four weeks later, mice were fed a high-fat, high-cholesterol, …
Authors
Pei Y; Chen X; Aboutouk D; Fuller MT; Dadoo O; Yu P; White EJ; Igdoura S; Trigatti BL
Journal
Arteriosclerosis Thrombosis and Vascular Biology, Vol. 34, No. suppl_1,
Publisher
Wolters Kluwer
Publication Date
May 2014
DOI
10.1161/atvb.34.suppl_1.669
ISSN
1079-5642