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Optimizing the Bacteriostatic and...
Journal article

Optimizing the Bacteriostatic and Cytocompatibility Properties of Poly(hexamethylene guanidine) Hydrochloride (PHMG) via the Guanidine/Alkane Ratio

Abstract

The emergence of "superbugs" is not only problematic and potentially lethal for infected subjects but also poses serious challenges for the healthcare system. Although existing antibacterial agents have been effective in some cases, the side effects and biocompatibility generally present difficulties. The development of new antibacterial agents is therefore urgently required. In this work, we have adapted a strategy for the improvement of …

Authors

Rao Y; Wang J; Wang H; Wang H; Gu R; Shen J; Hao Q; Brash JL; Chen H

Journal

Biomacromolecules, Vol. 23, No. 5, pp. 2170–2183

Publisher

American Chemical Society (ACS)

Publication Date

May 9, 2022

DOI

10.1021/acs.biomac.2c00233

ISSN

1525-7797