Prognostic factors associated with development of infected necrosis in patients with acute necrotizing or severe pancreatitis—A systematic review and meta-analysis

PURPOSE: Acute pancreatitis is a potentially life-threatening condition with a wide spectrum of clinical presentation and illness severity. An infection of pancreatic necrosis (IPN) results in a more than twofold increase in mortality risk as compared with patients with sterile necrosis. We sought to identify prognostic factors for the development of IPN among adult patients with severe or necrotizing pancreatitis. METHODS: We conducted this …