Journal article
Circulating cell free DNA and citrullinated histone H3 as useful biomarkers of NETosis in endometrial cancer
Abstract
BackgroundCancer mortality is mainly caused by organ failure and thrombotic events. It has been demonstrated that NETosis, a chromatin release mechanism implemented by neutrophils, may contribute to these lethal systemic effects. Our aim was to investigate NETosis biomarkers in endometrial cancer (EC).MethodsThe experiments were conducted on 21 healthy subjects (HS) with no gynecological conditions, and on 63 EC patients. To assess the presence …
Authors
Ronchetti L; Terrenato I; Ferretti M; Corrado G; Goeman F; Donzelli S; Mandoj C; Merola R; Zampa A; Carosi M
Journal
Journal of Experimental & Clinical Cancer Research, Vol. 41, No. 1,
Publisher
Springer Nature
DOI
10.1186/s13046-022-02359-5
ISSN
0392-9078