Journal article
Hydroxyzine Initiation Following Drug Safety Advisories on Cardiac Arrhythmias in the UK and Canada: A Longitudinal Cohort Study
Abstract
IntroductionRegulatory advisories on hydroxyzine and risk of QT prolongation and Torsade de pointes (TdP) were issued in the UK in April 2015 and Canada in June 2016. We hypothesized patients with risk factors for QT prolongation and TdP, compared with those without risk factors, would be less likely to initiate hydroxyzine in the UK and in British Columbia (BC), Canada, following advisories.MethodsWe conducted a longitudinal study with …
Authors
Morrow RL; Mintzes B; Souverein PC; Hallgreen CE; Ahmed B; Roughead EE; De Bruin ML; Kristiansen SB; Lexchin J; Kemp-Casey A
Journal
Drug Safety, Vol. 45, No. 6, pp. 623–638
Publisher
Springer Nature
Publication Date
June 2022
DOI
10.1007/s40264-022-01175-2
ISSN
0114-5916