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The Mirasol Evaluation of Reduction in Infections...
Journal article

The Mirasol Evaluation of Reduction in Infections Trial (MERIT): study protocol for a randomized controlled clinical trial

Abstract

BackgroundTransfusion-transmitted infections (TTIs) are a global health challenge. One new approach to reduce TTIs is the use of pathogen reduction technology (PRT). In vitro, Mirasol PRT reduces the infectious load in whole blood (WB) by at least 99%. However, there are limited in vivo data on the safety and efficacy of Mirasol PRT. The objective of the Mirasol Evaluation of Reduction in Infections Trial (MERIT) is to investigate whether …

Authors

Kasirye R; Hume HA; Bloch EM; Lubega I; Kyeyune D; Shrestha R; Ddungu H; Musana HW; Dhabangi A; Ouma J

Journal

Trials, Vol. 23, No. 1,

Publisher

Springer Nature

Publication Date

December 2022

DOI

10.1186/s13063-022-06137-8

ISSN

1468-6708