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Comparison of methods in the recovery of nucleic...
Journal article

Comparison of methods in the recovery of nucleic acids from archival formalin-fixed paraffin-embedded autopsy tissues

Abstract

Archival formalin-fixed paraffin-embedded (FFPE) human tissue collections are typically in poor states of storage across the developing world. With advances in biomolecular techniques, these extraordinary and virtually untapped resources have become an essential part of retrospective epidemiological studies. To successfully use such tissues in genomic studies, scientists require high nucleic acid yields and purity. In spite of the increasing …

Authors

Okello JBA; Zurek J; Devault AM; Kuch M; Okwi AL; Sewankambo NK; Bimenya GS; Poinar D; Poinar HN

Journal

Analytical Biochemistry, Vol. 400, No. 1, pp. 110–117

Publisher

Elsevier

Publication Date

May 2010

DOI

10.1016/j.ab.2010.01.014

ISSN

0003-2697