Journal article
Comparison of methods in the recovery of nucleic acids from archival formalin-fixed paraffin-embedded autopsy tissues
Abstract
Archival formalin-fixed paraffin-embedded (FFPE) human tissue collections are typically in poor states of storage across the developing world. With advances in biomolecular techniques, these extraordinary and virtually untapped resources have become an essential part of retrospective epidemiological studies. To successfully use such tissues in genomic studies, scientists require high nucleic acid yields and purity. In spite of the increasing …
Authors
Okello JBA; Zurek J; Devault AM; Kuch M; Okwi AL; Sewankambo NK; Bimenya GS; Poinar D; Poinar HN
Journal
Analytical Biochemistry, Vol. 400, No. 1, pp. 110–117
Publisher
Elsevier
Publication Date
May 2010
DOI
10.1016/j.ab.2010.01.014
ISSN
0003-2697