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Pandemic-response adenoviral vector and RNA...
Journal article

Pandemic-response adenoviral vector and RNA vaccine manufacturing

Abstract

Rapid global COVID-19 pandemic response by mass vaccination is currently limited by the rate of vaccine manufacturing. This study presents a techno-economic feasibility assessment and comparison of three vaccine production platform technologies deployed during the COVID-19 pandemic: (1) adenovirus-vectored (AVV) vaccines, (2) messenger RNA (mRNA) vaccines, and (3) the newer self-amplifying RNA (saRNA) vaccines. Besides assessing the baseline …

Authors

Kis Z; Tak K; Ibrahim D; Papathanasiou MM; Chachuat B; Shah N; Kontoravdi C

Journal

npj Vaccines, Vol. 7, No. 1,

Publisher

Springer Nature

DOI

10.1038/s41541-022-00447-3

ISSN

2059-0105