Reduced field-of-view diffusion tensor imaging together with optical coherence tomography in detecting alterations of retinal ganglion cell axons in patients with retinitis pigmentosa

Objective To investigate the damage of retinal ganglion cell (RGC) axons in retinitis pigmentosa (RP) quantitatively by using reduced-filed-of-view DTI (rfov-DTI) together with optical coherence tomography (OCT). Methods Thirty four patients(68 eyes,Patient group)and 33 healthy controls(66 eyes, Control group) were enrolled in this study. Measures of rfov-DTI and OCT of both eyes in all subjects were performed by 3.0 MRI. The difference of …