Abstract WP487: Retinal Vessel Tortuosity Correlates With White Matter Hyperintensities and Cerebral Microbleeds in Subjects With Cognitive Decline

Objective: Retinal microvasculature analysis is suitable to study cognitive disorders given retinal and brain vessels share similar properties. Using novel automated technologies, we aimed to investigate whether automatically-quantified retinal vascular changes from retinal fundus photographs predict brain imaging abnormalities in patients with cognitive impairment; and what specific retinal vascular parameters are more predictive of dementia. …