Journal article
STEM-17. CHARACTERIZATION OF THE CELL SURFACE PROTEOME IN RECURRENT GLIOBLASTOMA INITIATING CELLS
Abstract
Glioblastoma (GBM) is the most common and aggressive malignant primary brain tumor in humans, bearing an overwhelmingly poor prognosis and characterized by a diverse cellular phenotype and genetic heterogeneity. Despite multimodal therapy, patients on average experience relapse at 9 months and median survival rarely extends beyond 15 months. Treatment of human GBM with standard-of-care (SOC) chemo-radiotherapy invariably leads to resistance. …
Authors
Seyfrid M; Chokshi C; Kuhlmann L; Venugopal C; Vora P; Sinha A; Ignatchenko V; Macklin A; Kislinger T; Singh S
Journal
Neuro-Oncology, Vol. 19, No. suppl_6, pp. vi229–vi229
Publisher
Oxford University Press (OUP)
Publication Date
November 6, 2017
DOI
10.1093/neuonc/nox168.933
ISSN
1522-8517