Journal article
THER-14. SMALL MOLECULE INHIBITOR TARGETING SELF-RENEWAL AS A THERAPEUTIC OPTION FOR RECURRENT MEDULLOBLASTOMA
Abstract
Medulloblastoma (MB) is the most common pediatric brain tumor malignancy, and one of the leading causes of childhood cancer mortality. Often associated with tumor recurrence, relapsed MB patients are limited to palliation outwith the paucity of clinical trials available, carrying a mortality rate approaching 100%. Selectively targeting the MB stem cell population that evade conventional chemoradiotherapy and drive recurrence, can reduce the …
Authors
Adile A; Bakhshinyan D; Venugopal C; Subapanditha M; Weetall M; Davis T; Singh S
Journal
Neuro-Oncology, Vol. 21, No. Supplement_2, pp. ii117–ii117
Publisher
Oxford University Press (OUP)
Publication Date
April 23, 2019
DOI
10.1093/neuonc/noz036.221
ISSN
1522-8517