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Balanced Versus Unbalanced Fluid in Critically Ill...
Journal article

Balanced Versus Unbalanced Fluid in Critically Ill Children: Systematic Review and Meta-Analysis*

Abstract

OBJECTIVES: The ideal crystalloid fluid bolus therapy for fluid resuscitation in children remains unclear, but pediatric data are limited. Administration of 0.9% saline has been associated with hyperchloremic metabolic acidosis and acute kidney injury. The primary objective of this systematic review was to compare the effect of balanced versus unbalanced fluid bolus therapy on the mean change in serum bicarbonate or pH within 24 hours in …

Authors

Lehr AR; Rached-d'Astous S; Barrowman N; Tsampalieros A; Parker M; McIntyre L; Sampson M; Menon K

Journal

Pediatric Critical Care Medicine, Vol. 23, No. 3, pp. 181–191

Publisher

Wolters Kluwer

Publication Date

March 2022

DOI

10.1097/pcc.0000000000002890

ISSN

1529-7535