Journal article
Uptake and release of polyhexamethylene biguanide (PHMB) from hydrogel and silicone hydrogel contact lenses using a radiolabel methodology
Abstract
PURPOSE: The purpose of this study was to evaluate the uptake and release of radiolabelled polyhexamethylene biguanide (PHMB) on reusable daily wear contact lenses (CLs) over 7 days.
METHODS: Three silicone hydrogel (SH) contact lens materials (lotrafilcon B, balafilcon A, senofilcon A) and two conventional hydrogel (CH) materials (etafilcon A, omafilcon A) were examined. In experiment 1 (1-day study), CLs were soaked in 2 mL of phosphate …
Authors
Yee A; Phan C-M; Jones L
Journal
Contact Lens and Anterior Eye, Vol. 45, No. 5,
Publisher
Elsevier
Publication Date
October 2022
DOI
10.1016/j.clae.2022.101575
ISSN
1367-0484