Journal article
Inactivated and live-attenuated seasonal influenza vaccines boost broadly neutralizing antibodies in children
Abstract
The induction of broadly neutralizing antibodies (bNAbs) that target the hemagglutinin stalk domain is a promising strategy for the development of "universal" influenza virus vaccines. bNAbs can be boosted in adults by sequential exposure to heterosubtypic viruses through natural infection or vaccination. However, little is known about if or how bNAbs are induced by vaccination in more immunologically naive children. Here, we describe the …
Authors
Yegorov S; Celeste DB; Gomes KB; Ang JC; Vandenhof C; Wang J; Rybkina K; Tsui V; Stacey HD; Loeb M
Journal
Cell Reports Medicine, Vol. 3, No. 2,
Publisher
Elsevier
Publication Date
2 2022
DOI
10.1016/j.xcrm.2022.100509
ISSN
2666-3791