Journal article
Dysbetalipoproteinemia: Differentiating Multifactorial Remnant Cholesterol Disease From Genetic ApoE Deficiency
Abstract
CONTEXT: Dysbetalipoproteinemia (DBL) is characterized by the accumulation of remnant lipoprotein particles and associated with an increased risk of cardiovascular and peripheral vascular disease (PVD). DBL is thought to be mainly caused by the presence of an E2/E2 genotype of the apolipoprotein E (APOE) gene, in addition to environmental factors. However, there exists considerable phenotypic variability among DBL patients.
OBJECTIVE: The …
Authors
Paquette M; Bernard S; Paré G; Baass A
Journal
The Journal of Clinical Endocrinology & Metabolism, Vol. 107, No. 2, pp. 538–548
Publisher
The Endocrine Society
Publication Date
January 18, 2022
DOI
10.1210/clinem/dgab648
ISSN
0021-972X