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CircPVT1: a pivotal circular node intersecting...
Journal article

CircPVT1: a pivotal circular node intersecting Long Non-Coding-PVT1 and c-MYC oncogenic signals

Abstract

The role of circular RNAs in oncogenesis has begun to be widely studied in recent years, due to the significant impact that these molecules have in disease pathogenesis, as well as their potential for the future of innovative therapies. Moreover, due to their characteristically circular shape, circular RNAs are very resistant molecules to RNA degradation whose levels are easily assessed in body fluids. Accordingly, they represent an opportunity …

Authors

Palcau AC; Canu V; Donzelli S; Strano S; Pulito C; Blandino G

Journal

Molecular Cancer, Vol. 21, No. 1,

Publisher

Springer Nature

DOI

10.1186/s12943-022-01514-y

ISSN

1476-4598