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A Randomized Trial Comparing 3- versus 4-Monthly...
Journal article

A Randomized Trial Comparing 3- versus 4-Monthly Cardiac Monitoring in Patients Receiving Trastuzumab-Based Chemotherapy for Early Breast Cancer

Abstract

PURPOSE: The optimal frequency for cardiac monitoring of left ventricular ejection fraction (LVEF) in patients receiving trastuzumab-based therapy for early breast cancer (EBC) is unknown. We conducted a randomized controlled trial comparing 3- versus 4-monthly cardiac monitoring. PATIENTS AND METHOD: Patients scheduled to receive trastuzumab-containing cancer therapy for EBC with normal (>53%) baseline LVEF were randomized to undergo LVEF …

Authors

Dent S; Fergusson D; Aseyev O; Stober C; Pond G; Awan AA; McGee SF; Ng TL; Simos D; Vandermeer L

Journal

Current Oncology, Vol. 28, No. 6, pp. 5073–5083

Publisher

MDPI

DOI

10.3390/curroncol28060427

ISSN

1198-0052