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Compound Kushen Injection suppresses human breast...
Journal article

Compound Kushen Injection suppresses human breast cancer stem-like cells by down-regulating the canonical Wnt/β-catenin pathway

Abstract

BackgroundCancer stem cells (CSCs) play an important role in cancer initiation, relapse and metastasis. To date, no specific medicine has been found to target CSCs as they are resistant to most conventional therapies and proliferate indefinitely. Compound Kushen Injection (CKI) has been widely used for cancer patients with remarkable therapeutic effects in Chinese clinical settings for many years. This study focused on whether CKI could inhibit …

Authors

Xu W; Lin H; Zhang Y; Chen X; Hua B; Hou W; Qi X; Pei Y; Zhu X; Zhao Z

Journal

Journal of Experimental & Clinical Cancer Research, Vol. 30, No. 1,

Publisher

Springer Nature

Publication Date

12 2011

DOI

10.1186/1756-9966-30-103

ISSN

0392-9078