Journal article
Effects of Kaixinjieyu, a Chinese herbal medicine preparation, on neurovascular unit dysfunction in rats with vascular depression
Abstract
BackgroundKaixinjieyu (KJ), derived from Kaixin and Sini powder, is an effective Chinese herbal medicine preparation used in the treatment of vascular depression (VD). We hypothesize that broad antidepressant effect of KJ results from the improved neurovascular unit (NVU) function via neurogenesis, permeability of blood–brain barrier (BBB) and balance of the fibrinolytic system.MethodsA VD model of rat was established by chronic unpredictable …
Authors
Pan J; Lei X; Wang J; Huang S; Wang Y; Zhang Y; Chen W; Li D; Zheng J; Cui H
Journal
BMC Complementary Medicine and Therapies, Vol. 15, No. 1,
Publisher
Springer Nature
Publication Date
December 2015
DOI
10.1186/s12906-015-0808-z
ISSN
2662-7671