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Journal article

Peroxisome proliferator-activated receptor-γ agonist pioglitazone fails to attenuate renal fibrosis caused by unilateral ureteral obstruction in mice

Abstract

Renal tubulointerstitial fibrosis is the common ending of progreβsive renal disease. It is worth developing new ways to stop the progreβs of renal fibrosis. Peroxisome proliferator-activated receptor-γ (PPARγ) agonists have been studied to treat diabetic nephropathy, cisplatin-induced acute renal injury, ischemia reperfusion injury and adriamycin nephropathy. In this study, unilateral ureteral obstruction (UUO) was used to establish a different …

Authors

Zhang Y; Wang J; Zhou Q-D; Zhang C-H; Li Q; Huang S; Zhan J; Wang K; Liu Y-Y; Xu G

Journal

Current Medical Science, Vol. 36, No. 1, pp. 41–47

Publisher

Springer Nature

Publication Date

February 2016

DOI

10.1007/s11596-016-1539-1

ISSN

2096-5230