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Trends in Adaptive Design Methods in Dialysis...
Journal article

Trends in Adaptive Design Methods in Dialysis Clinical Trials: A Systematic Review

Abstract

RATIONALE & OBJECTIVE: Adaptive design methods are intended to improve the efficiency of clinical trials and are relevant to evaluating interventions in dialysis populations. We sought to determine the use of adaptive designs in dialysis clinical trials and quantify trends in their use over time. STUDY DESIGN: We completed a novel full-text systematic review that used a machine learning classifier (RobotSearch) for filtering randomized …

Authors

Judge C; Murphy R; Reddin C; Cormican S; Smyth A; O’Halloran M; O’Donnell MJ

Journal

Kidney Medicine, Vol. 3, No. 6, pp. 925–941

Publisher

Elsevier

Publication Date

November 2021

DOI

10.1016/j.xkme.2021.08.001

ISSN

2590-0595