Journal article
Gut microbiota-based vaccination engages innate immunity to improve blood glucose control in obese mice
Abstract
OBJECTIVE: Obesity and diabetes increase circulating levels of microbial components derived from the gut microbiota. Individual bacterial factors (i.e., postbiotics) can have opposing effects on blood glucose.
METHODS: We tested the net effect of gut bacterial extracts on blood glucose in mice using a microbiota-based vaccination strategy.
Authors
Duggan BM; Tamrakar AK; Barra NG; Anhê FF; Paniccia G; Wallace JG; Stacey HD; Surette MG; Miller MS; Sloboda DM
Journal
Molecular Metabolism, Vol. 55, ,
Publisher
Elsevier
Publication Date
January 2022
DOI
10.1016/j.molmet.2021.101404
ISSN
2212-8778