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Role of intestinal microbiota and metabolites on...
Journal article

Role of intestinal microbiota and metabolites on gut homeostasis and human diseases

Abstract

BackgroundA vast diversity of microbes colonizes in the human gastrointestinal tract, referred to intestinal microbiota. Microbiota and products thereof are indispensable for shaping the development and function of host innate immune system, thereby exerting multifaceted impacts in gut health.MethodsThis paper reviews the effects on immunity of gut microbe-derived nucleic acids, and gut microbial metabolites, as well as the involvement of …

Authors

Lin L; Zhang J

Journal

BMC Immunology, Vol. 18, No. 1,

Publisher

Springer Nature

Publication Date

12 2017

DOI

10.1186/s12865-016-0187-3

ISSN

1471-2172